JCCVS

Journal of Cardiology & Cardiovascular Surgery scientific, open-access, double-blind peer-reviewed journal covering a wide spectrum of topics in cardiology and cardiovascular surgery.

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Original Article
Biomechanical comparison of commercially pure titanium and Ti-6Al-4V grade 5 sternal plates under static and dynamic loading conditions
Aims: Secure sternal fixation following median sternotomy is essential to prevent postoperative complications such as pain, respiratory dysfunction, sternal dehiscence, and mediastinitis. While Ti-6Al-4V Grade 5 titanium is widely used due to its high static strength, its excessive rigidity and limited ductility may compromise anatomical adaptation and fatigue performance. Commercially pure (CP) titanium, with mechanical properties closer to 316L stainless steel, may offer improved ductility without sacrificing fixation stability. This study aimed to compare the biomechanical behavior of CP titanium and Ti-6Al-4V Grade 5 sternal plates under static and dynamic loading conditions simulating physiological respiratory forces.
Methods: Straight, six-hole locked sternal plates manufactured from CP titanium (Grade 2/4) and Grade 5 titanium were evaluated. Static three-point bending tests and dynamic fatigue tests were performed using an Instron universal testing machine. A peak load of 250 N was applied to simulate clinically relevant sternal dehiscence forces, followed by cyclic loading up to 1,000,000 cycles at physiological frequencies. Load–displacement behavior, yield strength, displacement, and failure modes were analyzed and statistically compared.
Results: All constructs demonstrated plastic deformation without screw loosening, pull-out, or screw fracture. Catastrophic plate failure occurred exclusively in Grade 5 titanium plates, characterized by a shorter plastic deformation phase and abrupt fracture at the screw hole adjacent to the bending zone. In contrast, CP titanium plates exhibited prolonged plastic deformation without catastrophic failure under the same loading conditions. After 1 million fatigue cycles at 250 N, both materials maintained construct integrity, with no statistically significant difference in post-fatigue displacement (P > 0.05).
Conclusion: CP titanium sternal plates provide biomechanical performance comparable to Grade 5 titanium under clinically relevant static and dynamic loads while offering superior ductility and anatomical adaptability. These findings suggest that CP titanium represents a safe and clinically advantageous alternative to Grade 5 titanium for sternal fixation, particularly in anatomically complex and dynamically loaded environments.


1. Beyazal OF, Yanartaş M. Which sternal closure technique is more beneficial in cardiac surgery: simple wire, figure-of-8, or their combination? Braz J Cardiovasc Surg. 2025;40(6):e20250011. doi:10. 21470/1678-9741-2025-0011
2. Maeßen T, Korir N, Van de Velde M, et al. Pain management after cardiac surgery via median sternotomy: a systematic review with procedure-specific postoperative pain management (PROSPECT) recommendations. Eur J Anaesthesiol. 2023;40(10):758-768. doi:10.1097/EJA.0000000000001881
3. Deranlot J, Maurel N, Diop A, et al. Abrasive properties of braided polyblend sutures in cuff tendon repair: an in vitro biomechanical study exploring regular and tape sutures.Arthroscopy. 2014;30(12):1569-1573. doi:10.1016/j.arthro.2014.06.018
4. Raman J, Song DH, Bolotin G, Jeevanandam V. Sternal closure with titanium plate fixation--a paradigm shift in preventing mediastinitis. Interact Cardiovasc Thorac Surg. 2006;5(4):336-339. doi:10.1510/icvts. 2005.121863
5. Quinn J, McFadden R, Chan CW, Carson L. Titanium for orthopedic applications: an overview of surface modification to ımprove biocompatibility and prevent bacterial biofilm formation.iScience. 2020;23(11):101745. doi:10.1016/j.isci.2020.101745
6. Jorge JR, Barão VA, Delben JA, Faverani LP, Queiroz TP, Assunção WG. Titanium in dentistry: historical development, state of the art and future perspectives.J Indian Prosthodont Soc. 2013;13(2):71-77. doi:10. 1007/s13191-012-0190-1
7. Olin C. Titanium in cardiac and cardiovascular applications. In: Brunette DM, Tengvall P, Textor M, Thomsen P, eds. Titanium in Medicine: Material Science, Surface Science, Engineering, Biological Responses and Medical Applications. Berlin, Heidelberg: Springer Berlin Heidelberg; 2001:889-907.
8. Elias CN, Lima JHC, Valiev R, Meyers MA. Biomedical applications of titanium and its alloys. JOM. 2008;60(3):46-49. doi:10.1007/S11837-008-0031-1
9. Niinomi M. Mechanical biocompatibilities of titanium alloys for biomedical applications. J Mech Behav Biomed Mater. 2008;1(1):30-42. doi:10.1016/j.jmbbm.2007.07.001
10. Valiev R. Nanostructuring of metals by severe plastic deformation for advanced properties.Nat Mater. 2004;3(8):511-516. doi:10.1038/nmat 1180
11. Schmidutz F, Agarwal Y, Müller PE, Gueorguiev B, Richards RG, Sprecher CM. Stress-shielding induced bone remodeling in cementless shoulder resurfacing arthroplasty: a finite element analysis and in vivo results.J Biomech. 2014;47(14):3509-3516. doi:10.1016/j.jbiomech.2014. 08.029
12. McGregor WE, Trumble DR, Magovern JA. Mechanical analysis of midline sternotomy wound closure.J Thorac Cardiovasc Surg. 1999; 117(6):1144-1150. doi:10.1016/s0022-5223(99)70251-5
13. Casha AR, Gauci M, Yang L, Saleh M, Kay PH, Cooper GJ. Fatigue testing median sternotomy closures.Eur J Cardiothorac Surg. 2001; 19(3):249-253. doi:10.1016/s1010-7940(01)00584-x
Volume 4, Issue 1, 2026
Page : 1-5
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