JCCVS
Journal of Cardiology & Cardiovascular Surgery

Journal of Cardiology & Cardiovascular Surgery scientific, open-access, double-blind peer-reviewed journal covering a wide spectrum of topics in cardiology and cardiovascular surgery.

eISSN: 2980-1397
Creative Commons CC BY-NC-ND 4.0 International License.
EndNote Style

Online Manuscript System

Index
Original Article
Investigation of the relationship between nutrition and coronary slow flow-coronary ectasia in patients with acute coronary syndrome
Abstract
Aims: It is known that malnutrition is associated with various diseases and poor prognosis, but the relationship of this condition with slow coronary flow and coronary ectasia is not clearly known. In our study, we tried to examine the relationship between malnutrition and slow flow-coronary ectasia in ACS (acute coronary syndrome) patients.
Methods: We examined the relationship between CONUT score, NRI score and PNI score in patients who underwent coronary angiography due to ACS and were found to have coronary ectasia-slow flow.
Results: According to the Conut score, malnutrition was not detected in 57% of the patients, but mild malnutrition was detected in 30%, moderate malnutrition in 10% and severe malnutrition in 1 patient; according to the PNI score, malnutrition was not detected in 61% of the patients, but moderate malnutrition was detected in 19%, severe malnutrition was detected in 18% and coronary slow flow-ectasia was detected in 44% of these patients. (p=0.003, p=0.002)
Conclusion: Malnutrition is associated with slow flow and coronary ectasia in patients with acute coronary syndrome. Nutritional assessment and corrective measures are vital for this patient group. Clinical studies are needed to prospectively evaluate these patients.

Keywords : Conut score, NRI score, PNI score, malnutrition

Download Article


1. Szummer K, Jernberg T, Wallentin L. From early pharmacology to recent pharmacology interventions in acute coronary syndromes: JACC state-of-the-art review. J Am Coll Cardiol. 2019;74(12):1618-1636.
2. Tambe AA, Demany MA, Zimmerman HA, Mascarenhas E. Angina pectoris and slow flow velocity of dye in coronary arteries-a new angiographic finding. Am Heart J. 1972;84(1):66 71.
3. Mangieri E, Macchiarelli G, Ciavolella M, et al. Slow coronary flow: clinical and histopathological features in patients with otherwise normal epicardial coronary arteries. Cathet Cardiovasc Diagn. 1996;37(4):375-381. doi:10.1002/(SICI)1097-0304(199604)37:4<375::AID-CCD7>3.0.CO;2-8
4. Zhang Q, Qian L, Liu T, et al. Prevalence and prognostic value of malnutrition among elderly cancer patients using three scoring systems. Front Nutr. 2021;8:738550. doi: 10.3389/fnut.2021.738550
5. Freeman AM, Morris PB, Barnard N, et al. Trending cardiovascular nutrition controversies. J Am Coll Cardiol. 2017;69(9):1172-1187.
6. Zhang HX, Ye N, Peng F, Pan LJ, Shi YJ, Gong H. Abnormality in coronary slow flow phenomenon detected by nailfold microcirculation microanalysis.Chin Med J (Engl). 2021;134(11):1370-1372.
7. Lamtai, M., Fihri, Y., Faid, S., Nabil, L., Britel, D., Faliouni, H., … & Benyass, A. (2024). Coronary artery ectasia: case reports and literature review. Cureus. 2024;16(6):e62011.
8. Ignacio de Ulibarri J, Gonzalez-Madrono A, de Villar NG, et al. CONUT: a tool for controlling nutritional status. First validation in a hospital population. Nutr Hosp. 2005;20(1):38-45.
9. Buzby GP, Williford WO, Peterson OL, et al. A randomized clinical trial of total parenteral nutrition in malnourished surgical patients: the rationale and impact of previous clinical trials and pilot study on protocol design. Am J Clin Nutr. 1988;47(2 Suppl):357-365.
10. Bouillanne O, Morineau G, Dupont C, et al. Geriatric nutritional risk index: a new index for evaluating at-risk elderly medical patients. Am J Clin Nutr. 2005;82(4):777-783.
11. Minamisawa M, Seidelmann SB, Claggett B, et al. Impact of malnutrition using geriatric nutritional risk index in heart failure with preserved ejection fraction. J Am Coll Cardiol HF. 2019;7(8):664-675.
12. Buzby GP, Mullen JL, Matthews DC, Hobbs CL, Rosato EF. Prognostic nutritional index in gastrointestinal surgery. Am J Surg. 1980;139(1):160-167. doi: 10.1016/0002-9610(80)90246-9
13. Sze S, Pellicori P, Kazmi S, et al. Prevalence and prognostic significance of malnutrition using 3 scoring systems among outpatients with heart failure: a comparison with body-mass index. JACC Heart Fail. 2018;6(6):476-486. doi:10.1016/j.jchf.2018.02.018
14. Tonet E, Campo G, Maietti E, et al. Nutritional status and all-cause mortality in older adults with acute coronary syndrome. Clin Nutr. 2019; 38(6):2956-2957.
15. Yoo SH, Kook HY, Hong YJ, Kim JH, Ahn Y, Jeong MH. Influence of undernutrition at admission on clinical outcomes in patients with acute myocardial infarction. J Cardiol. 2017;69(3):555-560.
16. Basta G, Chatzianagnostou K, Paradossi U, et al. The prognostic impact of objective nutritional indices in elderly patients with ST-elevation myocardial infarction undergoing primary coronary intervention. Int J Cardiol. 2016;221:987-992.
17. Liu J, Huang Z, Huang H, et al. Malnutrition in patients with coronary artery disease: prevalence and mortality in a 46,485 Chinese cohort study. Nutr Metab Cardiovasc Dis. 2022;32(5):1186-1194. doi:10.1016/j.numecd. 2021.12.023
18. Kalantar-Zadeh K, Anker SD, Horwich TB, Fonarow GC. Nutritional and anti-inflammatory interventions in chronic heart failure. Am J Cardiol. 2008;101(11A):89E-103E.
19. Lehrke M, Millington SC, Lefterova M, et al. CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans. J Am Coll Cardiol. 2007;49(4):442-449.
20. Sueta D, Hokimoto S, Sakamoto K, et al. Validation of the high mortality rate of malnutritioninflammation-atherosclerosis syndrome: community-based observational study. Int J Cardiol. 2017;230:97-102.
21. Yousufuddin M, Takahashi PY, Major B, et al. Association between hyperlipidemia and mortality after incident acute myocardial infarction or acute decompensated heart failure: a propensity score matched cohort study and a meta-analysis. BMJ Open. 2019;9(12):e028638.
22. Dahabreh IJ, Kent DM. Index event bias as an explanation for the paradoxes of recurrence risk research. JAMA. 2011;305(8):822-823.
23. Belabed L, Charrueau C, Besson V, et al. Impairment of lymphocyte function in headinjured rats: effects of standard and immuneenhancing diets for enteral nutrition. Clin Nutr. 2006;25(5):832-841.
24. Rauchhaus M, Clark AL, Doehner W, et al. The relationship between cholesterol and survival in patients with chronic heart failure. J Am Coll Cardiol. 2003;42(11):1933-1940.
25. Ridker PM, Rifai N, Rose L, Buring JE, Cook NR. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med. 2002;347(20):1557-1565.
26. Nakagomi A, Seino Y, Noma S, et al. Relationships between the serum cholesterol levels, production of monocyte proinflammatory cytokines and long-term prognosis in patients with chronic heart failure. Intern Med. 2014;53(21):2415-2424.
27. Bandayrel K, Wong S. Systematic literature review of randomized control trials assessing the effectiveness of nutrition interventions in community-dwelling older adults. J Nutr Educ Behav. 2011;43(4):251-262.
28. Schuetz P, Fehr R, Baechli V, et al. Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial. Lancet. 2019;393(10188):2312-2321.
29. Kumar S, Behl T, Sachdeva M, et al. Implicating the effect of ketogenic diet as a preventive measure to obesity and diabetes mellitus. Life Sci. 2021;264: 118661. doi:10.1016/j.lfs.2020.118661
30. Jenkins DJA, Dehghan M, Mente A, et al. Glycemic index, glycemic load, and cardiovascular disease and mortality. N Engl J Med. 2021;385(4):379-380. doi:10.1056/NEJMoa2007123
31. Krustev T, Milushewa P, Tachkov K, Mitov K, Petrova G. Evaluation of potentially inappropriate medication in older patients with cardiovascular diseasesSTOPP/START-based study. Front Public Health. 2022;10:1023171. doi:10.3389/ fpubh.2022.1023171
32. Vesa CM, Bungau SG. Novel molecules in diabetes mellitus, dyslipidemia and cardiovascular disease. Int J Mol Sci. 2023;24(4):4029. doi:10.3390/ijms2404402
33. Manu N, Tripathy N, Divya N. (2020). A rare case of “coronary slow-flow phenomena” in an aviator: an approach to aeromedical disposition - a case report. Indian J Aerospace Med. 2020;64(1):46-49.
34. Tony H, Meng K, Wu B, Zeng Q. Among ectasia patients with coexisting coronary artery disease, tımı frame count correlates with ectasia size and markis type ıv ıs the commonest.Cardiol Res Pract. 2015;2015:282170. doi:10.1155/2015/282170
Article available in :
Volume 2, Issue 4, 2024
Page : 89-95
https://doi.org/10.51271/JCCVS-0045
Article Information
Received : 08 Ara 2024
Accepted : 22 Ara 2024
Published : 29 Ara 2024
Corresponding Author :

Ahmet Ferhat Kaya: Department of Cardiology, Van Regional Training and Research Hospital, Van, Turkiye

[email protected]
Citation : Kaya AF. Investigation of the relationship between nutrition and coronary slow flow-coronary ectasia in patients with acute coronary syndrome. J Cardiol Cardiovasc Surg. 2024;2(4):89-95.

Read: 57
Cited: 0
Download : 61
_Footer