JCCVS
Journal of Cardiology & Cardiovascular Surgery

Journal of Cardiology & Cardiovascular Surgery scientific, open-access, double-blind peer-reviewed journal covering a wide spectrum of topics in cardiology and cardiovascular surgery.

eISSN: 2980-1397
Creative Commons CC BY-NC-ND 4.0 International License.
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Original Article
The impact of systemic immune inflammation index and neutrophil/lymphocyte ratio on mortality in patients undergoing surgery for infective endocarditis
Abstract
Aims: Infective endocarditis (IE) is a severe cardiac pathology associated with high morbidity and mortality. Early identification of disease severity and mortality risk using simple, rapid, and cost-effective tests can significantly improve clinical outcomes. This study aims to provide clinicians with valuable information on the prognostic importance of SIII and NLR in the management of IE patients and to guide potentially more effective perioperative interventions.
Methods: This study retrospectively investigates the relationship between the Systemic Immune Inflammation Index (SIII), Neutrophil/Lymphocyte Ratio (NLR), and mortality in patients who underwent surgical treatment for IE between March 2020 and November 2023. A total of 100 patients over the age of 18 were included in the study. Data were collected on various clinical parameters, and statistical analyses were performed using SPSS 26.0.
Results: Patients who experienced mortality had significantly higher mean SIII (1953.6 vs. 1352.4, p=0.003) and NLR (8.5 vs. 5.7, p=0.007) values than those who survived. These high indices in the mortality group suggest a stronger inflammatory response and immune dysregulation, making SIII and NLR useful indicators for assessing the prognosis of patients with infective endocarditis.
Conclusion: The study underscores the potential of these indices as reliable markers for predicting mortality and disease severity in IE, ultimately aiding in better patient stratification and management.

Keywords : Infective endocarditis, systemic immune inflammation index, neutrophil/lymphocyte ratio, mortality, prognostic markers

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Article available in :
Volume 2, Issue 4, 2024
Page : 83-88
https://doi.org/10.51271/JCCVS-0044
Article Information
Received : 08 Ara 2024
Accepted : 21 Ara 2024
Published : 29 Ara 2024
Corresponding Author :

Abdullah Burak Balcı: Department of Cardiovascular Surgery, Başakşehir Çam and Sakura City Hospital, İstanbul, Turkiye

[email protected]
Citation : Balcı AB, Rahman ÖF, Kolay G, Güneş G, Yazıcı S. The impact of systemic immune inflammation index and neutrophil/lymphocyte ratio on mortality in patients undergoing surgery for infective endocarditis. J Cardiol Cardiovasc Surg. 2024;2(4):83-88.

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