JCCVS
Journal of Cardiology & Cardiovascular Surgery

Journal of Cardiology & Cardiovascular Surgery scientific, open-access, double-blind peer-reviewed journal covering a wide spectrum of topics in cardiology and cardiovascular surgery. This journal is indexed by indices that are considered international scientific journal indices (DRJI, ESJI, OAJI, etc.). According to the current Associate Professorship criteria, it is within the scope of International Article 1-d. Each article published in this journal corresponds to 5 points.

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Original Article
Investigation of serum copeptin levels in patients with congestive heart failure
Abstract
Aims: Congestive heart failure (CHF) is characterized by symptoms and signs of volume overload and tissue perfusion insufficiency and accompanied by neurohormonal activation. Copeptin is a part of pre-pro-vasopressin and synthesized in equal molar amounts with vasopressin. We aimed to evaluate the sensitivity and specificity of copeptin in indicating the diagnostic value of CHF
Methods: This retrospective study included a total of 80 patients including 40 with heart failure and 40 healthy individuals. The groups were compared in terms of demographic features, laboratory findings including copeptin levels.
Results: There was no statistically significant difference between the groups in terms of gender (p>0.05). Age, hypertension, diabetes mellitus, smoking were statistically significantly higher in the heart failure group compared to the control group (p<0.05). In both groups, serum copeptin levels were higher in men than in women. Copeptin levels in the heart failure group were statistically significantly higher than in the control group (p<0.05). In the heart failure group, there was a negative correlation between serum copeptin levels and age, gender, hypertension, smoking, HDL cholesterol, hematocrit, creatinine levels.
Conclusion: Copeptin is a good indicator of the course of the disease in patients with heart failure.

Keywords : Congestive heart failure, copeptin, neurohormonal activation

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Article available in :
Volume 2, Issue 2, 2024
Page : 27-30
https://doi.org/10.51271/JCCVS-0030
Article Information
Received : 10 Haz 2024
Accepted : 26 Haz 2024
Published : 29 Haz 2024
Corresponding Author :

Zülfiye Kuzu: Department of Cardiology, Kayseri City Hospital, Kayseri, Turkiye

[email protected]
Citation : Kuzu Z, Kaya OK, Akgün AN, Solmaz H, Karataş M, Yavuzkır MF. Investigation of serum copeptin levels in patients with congestive heart failure. J Cardiol Cardiovasc Surg. 2024;2(2):27-30.

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